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Beyond benzoyl peroxide and antibiotics, what's new in acne?

• A (Dermatologist): Topical retinoids remain first-line, but adherence is poor due to irritation. New formulations (microsphere, encapsulated) and lower concentrations (0.025% tretinoin) improve tolerability. Also, topical clascoterone (Winlevi)—the first new mechanism in 40 years—blocks androgen receptors in the skin.

• B (Researcher): The microbiome is the frontier. Cutibacterium acnes phages—viruses that specifically kill acne-causing strains while leaving beneficial strains—are in Phase 2 trials. Also, topical niacinamide and zinc reduce inflammation without antibiotics.

• C (Pharmacist): Oral antibiotics (doxycycline, minocycline) are overprescribed. Long-term use drives resistance and destroys gut health. We need more prescribing of topical alternatives and spironolactone for adult female acne.

• D (Patient): I've tried everything for my hormonal acne—birth control, Spiro, topical creams. Accutane (isotretinoin) worked but the side effects (dry eyes, joint pain, mood changes) were brutal. We need a systemic treatment that isn't so toxic. Also, insurance should cover…

Welcome to the group!

AI Maturity is quickly increasing ...

• In 2022 we started with LLM's

• 2023 LLM's in ChatApps as Human Augmentation

• 2024 Single AI Agents as Task Automation

• 2025 Multi-Agent Systems (MAS) as AI for process coordination

• 2026 we are set to see AI for ontological learning and coordination - Multi-Agent + Data Fabrics ramp up into control systems - SLM's for Distributed Edge devices to decentralize compute usage

This is a hot topic of engagement. Both businesses and AI Makers are traveling this road simultaneously.

• Add your insights on this trend in your domain.

• Share thought engaging commentary on where you see it going next

Welcome to the group!

AI Agents have become the method of building an autonomous business operations. Whether in RevOps, ITOps, BuildOps, BusOps, or AnyOps, AI Agents are taking over work, unbundling tasks from workers, and restructuring how companies do business. What insights do you bring to the table in your Ops area? Do you have a blueprint for for changing the system in your Ops area?

You can connect with other members, get updates and share videos.

Welcome to the group!

Jobs are quickly becoming affected by the use of AI as automation in the workforce. At the same time workforce models are changing from hierarchical to flattened. It may be that you have some insights that could help others.

You can connect with other members, get updates and share videos.

Welcome to our group AI's Effect on Jobs! A space for us to connect and share with each other. Start by posting your thoughts, sharing media, or creating a poll.

Welcome to our group AI Maturity - Augment, Automate, & Control Systems! A space for us to connect and share with each other. Start by posting your thoughts, sharing media, or creating a poll.